ELASPIC home << Job #oncokb << Q9UM73.M1328I
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q9UM73.M1328I

Detailed results for job #oncokb produced by ELASPIC
Q9UM73, ALK tyrosine kinase receptor:
M1328I
1
1620
Pkinase_Tyr
MAP3K4, Mitogen-activated protein kinase kinase kinase 4:
1
1608
Pkinase
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Protein: Q9UM73 | MAP3K4 | Cofactors | All
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Q9UM73.M1328I

Completed successfully

Protein, domain: Q9UM73 Pkinase_Tyr

Interacting with: MAP3K4 Pkinase

PDB templates used: 3lvp_C, 3lvp_B

Seq identity: 0.461, 0.237 Model score: 0.350

ELASPIC ΔΔG: 1.563

ELASPIC2 (EL2) score: 1.439

Mutation run by user.

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Citation

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