ELASPIC home << Job #oncokb << Q9UM73.E1384K
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

Q9UM73.E1384K

Detailed results for job #oncokb produced by ELASPIC
Q9UM73, ALK tyrosine kinase receptor:
E1384K
1
1620
Pkinase_Tyr
MYLK isoform 2, Isoform 2 of Myosin light chain kinase, smooth muscle:
1
1845
I-..
I-..
I-..
I-set
I-..
I-..
I..
fn3
Pkinase
I-..
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Q9UM73.E1384K

Completed successfully

Protein, domain: Q9UM73 Pkinase_Tyr

Interacting with: MYLK isoform 2 Pkinase

PDB templates used: 2xzs_A, 2xzs_B

Seq identity: 0.263, 0.462 Model score: 1.101

ELASPIC ΔΔG: 1.273

ELASPIC2 (EL2) score: 0.129

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.