ELASPIC home << Job #oncokb << Q9UM73.C1156F
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

Q9UM73.C1156F

Detailed results for job #oncokb produced by ELASPIC
Q9UM73, ALK tyrosine kinase receptor:
C1156F
1
1620
Pkinase_Tyr
MYLK isoform 4, Isoform 3B of Myosin light chain kinase, smooth muscle:
1
1794
I-..
I-..
I-set
I-..
I-..
I-..
I-..
fn3
Pkinase
I-..
Select affected interaction:

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Q9UM73.C1156F

Completed successfully

Protein, domain: Q9UM73 Pkinase_Tyr

Interacting with: MYLK isoform 4 Pkinase

PDB templates used: 2zm3_B, 2zm3_C

Seq identity: 0.444, 0.261 Model score: 0.646

ELASPIC ΔΔG: 1.963

ELASPIC2 (EL2) score: 0.587

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

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