ELASPIC home << Job #oncokb << Q9UM73.C1156F
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q9UM73.C1156F

Detailed results for job #oncokb produced by ELASPIC
Q9UM73, ALK tyrosine kinase receptor:
C1156F
1
1620
Pkinase_Tyr
AAPK1 isoform 2, Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1:
1
574
Pkinase
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Q9UM73.C1156F

Completed successfully

Protein, domain: Q9UM73 Pkinase_Tyr

Interacting with: AAPK1 isoform 2 Pkinase

PDB templates used: 3h4j_A, 3h4j_B

Seq identity: 0.213, 0.559 Model score: 0.319

ELASPIC ΔΔG: 1.679

ELASPIC2 (EL2) score: -0.171

Mutation run by user.

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Citation

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