ELASPIC home << Job #oncokb << Q9NYV4.R882L
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q9NYV4.R882L

Detailed results for job #oncokb produced by ELASPIC
Q9NYV4, Cyclin-dependent kinase 12:
R882L
1
1490
Pkinase
CDK13 isoform 2, Isoform 2 of Cyclin-dependent kinase 13:
1
1452
Pkinase
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Q9NYV4.R882L

Completed successfully

Protein, domain: Q9NYV4 Pkinase

Interacting with: CDK13 isoform 2 Pkinase

PDB templates used: 4au8_A, 4au8_B

Seq identity: 0.380, 0.393 Model score: 0.555

ELASPIC ΔΔG: 1.788

ELASPIC2 (EL2) score: 1.774

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

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