ELASPIC home << Job #oncokb << Q9H334.R514C
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q9H334.R514C

Detailed results for job #oncokb produced by ELASPIC
Q9H334, Forkhead box protein P1:
R514C
1
677
Fork_head
FOXP2 isoform 9, Isoform 9 of Forkhead box protein P2:
1
732
Fork_head
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Q9H334.R514C

Completed successfully

Protein, domain: Q9H334 Fork_head

Interacting with: FOXP2 isoform 9 Fork_head

PDB templates used: 2a07_I, 2a07_H

Seq identity: 0.901, 1.000 Model score: -1.667

ELASPIC ΔΔG: 0.661

ELASPIC2 (EL2) score: 2.131

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

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