ELASPIC home << Job #oncokb << Q969H0.R505C
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

Q969H0.R505C

Detailed results for job #oncokb produced by ELASPIC
Q969H0, F-box/WD repeat-containing protein 7:
R505C
1
707
F-box-like
WD40
K1875 isoform 2, Isoform 2 of WD repeat-containing protein KIAA1875:
1
837
WD40
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Q969H0.R505C

Completed successfully

Protein, domain: Q969H0 WD40

Interacting with: K1875 isoform 2 WD40

PDB templates used: 3rfg_B, 3rfg_A

Seq identity: 0.251, 0.286 Model score: 1.913

ELASPIC ΔΔG: 0.451

ELASPIC2 (EL2) score: 2.687

Mutation in databases: COSMIC, COSMIC, COSMIC, COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.