ELASPIC home << Job #oncokb << Q92889.S786F
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

Q92889.S786F

Detailed results for job #oncokb produced by ELASPIC
Q92889, DNA repair endonuclease XPF:
S786F
1
916
ERCC4
ERCC4, DNA repair endonuclease XPF:
1
916
ERCC4
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Model: Wild-type | Mutant | Both
Protein: Q92889 | ERCC4 | Cofactors | All
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Q92889.S786F

Completed successfully

Protein, domain: Q92889 ERCC4

Interacting with: ERCC4 ERCC4

PDB templates used: 2bgw_A, 2bgw_B

Seq identity: 0.287, 0.289 Model score: -1.174

ELASPIC ΔΔG: 0.915

ELASPIC2 (EL2) score: 0.898

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.