ELASPIC home << Job #oncokb << Q15831.L67P
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

Q15831.L67P

Detailed results for job #oncokb produced by ELASPIC
Q15831, Serine/threonine-protein kinase STK11:
L67P
1
433
Pkinase
FKBP5 isoform 2, Isoform 2 of Peptidyl-prolyl cis-trans isomerase FKBP5:
1
268
FKBP_C
FKBP_C
Select affected interaction:

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Q15831.L67P

Completed successfully

Protein, domain: Q15831 Pkinase

Interacting with: FKBP5 isoform 2 FKBP_C

PDB templates used: 4c02_A, 4c02_B

Seq identity: 0.244, 0.500 Model score: 1.202

ELASPIC ΔΔG: 7.698

ELASPIC2 (EL2) score: 2.153

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.