ELASPIC home << Job #oncokb << Q15831.L67P
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

Q15831.L67P

Detailed results for job #oncokb produced by ELASPIC
Q15831, Serine/threonine-protein kinase STK11:
L67P
1
433
Pkinase
CAB39L, Calcium-binding protein 39-like:
1
337
Mo25
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Model: Wild-type | Mutant | Both
Protein: Q15831 | CAB39L | Cofactors | All
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Q15831.L67P

Completed successfully

Protein, domain: Q15831 Pkinase

Interacting with: CAB39L Mo25

PDB templates used: 3gni_B, 3gni_A

Seq identity: 0.221, 0.816 Model score: -0.262

ELASPIC ΔΔG: 1.483

ELASPIC2 (EL2) score: 1.324

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.