ELASPIC home << Job #oncokb << Q15831.L67P
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

Q15831.L67P

Detailed results for job #oncokb produced by ELASPIC
Q15831, Serine/threonine-protein kinase STK11:
L67P
1
433
Pkinase
FKBP5, Peptidyl-prolyl cis-trans isomerase FKBP5:
1
457
FKBP_C
FKBP_C
TPR_1
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Model: Wild-type | Mutant | Both
Protein: Q15831 | FKBP5 | Cofactors | All
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Q15831.L67P

Completed successfully

Protein, domain: Q15831 Pkinase

Interacting with: FKBP5 FKBP_C

PDB templates used: 4c02_A, 4c02_B

Seq identity: 0.244, 0.279 Model score: 1.367

ELASPIC ΔΔG: 5.665

ELASPIC2 (EL2) score: 2.243

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.