ELASPIC home << Job #oncokb << Q15831.I177N
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

Q15831.I177N

Detailed results for job #oncokb produced by ELASPIC
Q15831, Serine/threonine-protein kinase STK11:
I177N
1
433
Pkinase
KS6B1 isoform 2, Isoform Alpha II of Ribosomal protein S6 kinase beta-1:
1
502
Pkinase+Pkinase_C
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Q15831.I177N

Completed successfully

Protein, domain: Q15831 Pkinase

Interacting with: KS6B1 isoform 2 Pkinase+Pkinase_C

PDB templates used: 3a60_B, 3a60_A

Seq identity: 0.272, 0.916 Model score: 0.469

ELASPIC ΔΔG: 1.379

ELASPIC2 (EL2) score: 2.006

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.