ELASPIC home << Job #oncokb << Q15831.H174R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q15831.H174R

Detailed results for job #oncokb produced by ELASPIC
Q15831, Serine/threonine-protein kinase STK11:
H174R
1
433
Pkinase
PRKAA2, 5'-AMP-activated protein kinase catalytic subunit alpha-2:
1
552
Pkinase
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Protein: Q15831 | PRKAA2 | Cofactors | All
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Q15831.H174R

Completed successfully

Protein, domain: Q15831 Pkinase

Interacting with: PRKAA2 Pkinase

PDB templates used: 3dae_A, 3dae_B

Seq identity: 0.353, 0.566 Model score: 0.218

ELASPIC ΔΔG: 1.370

ELASPIC2 (EL2) score: 2.151

Mutation in databases: UniProt, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.