ELASPIC home << Job #oncokb << Q15303.S303Y
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q15303.S303Y

Detailed results for job #oncokb produced by ELASPIC
Q15303, Receptor tyrosine-protein kinase erbB-4:
S303Y
1
1308
Pkinase_Tyr
Furin..
Recep_L..
Recep_L_..
GF_rec..
ERBB3, Receptor tyrosine-protein kinase erbB-3:
1
1342
Pkinase_Tyr
Recep_..
Furin-l..
Recep_L_..
GF_re..
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Protein: Q15303 | ERBB3 | Cofactors | All
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Q15303.S303Y

Completed successfully

Protein, domain: Q15303 Furin-like

Interacting with: ERBB3 GF_recep_IV

PDB templates used: 3u7u_B, 3u7u_A

Seq identity: 0.975, 0.550 Model score: 1.437

ELASPIC ΔΔG: 0.529

ELASPIC2 (EL2) score: 0.886

Mutation in databases: UniProt, COSMIC.

Download:  PDBwt   | PDBmut

Citation

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