ELASPIC home << Job #oncokb << Q14790.G325A
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q14790.G325A

Detailed results for job #oncokb produced by ELASPIC
Q14790, Caspase-8:
G325A
1
479
DED
DED
Peptidase_C14

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Q14790.G325A

Completed successfully

Protein, domain: Q14790 Peptidase_C14

Type: Core (stability)

PDB template used: 4jj7_A

Seq identity: 1.000 Model score: -0.904

ELASPIC ΔΔG: 0.855

ELASPIC2 (EL2) score: -0.122

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.