ELASPIC home << Job #oncokb << Q14145.S243C
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q14145.S243C

Detailed results for job #oncokb produced by ELASPIC
Q14145, Kelch-like ECH-associated protein 1:
S243C
1
624
BTB+BACK
Kelch_1

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Q14145.S243C

Completed successfully

Protein, domain: Q14145 BTB+BACK

Type: Core (stability)

PDB template used: 4hxi_A

Seq identity: 0.371 Model score: 0.628

ELASPIC ΔΔG: 0.336

ELASPIC2 (EL2) score: 1.048

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.