ELASPIC home << Job #oncokb << Q13485.R361C
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q13485.R361C

Detailed results for job #oncokb produced by ELASPIC
Q13485, Mothers against decapentaplegic homolog 4:
R361C
1
552
MH1
MH2
Q68DB7, Putative uncharacterized protein DKFZp781C1895:
1
465
MH1
MH2
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Protein: Q13485 | Q68DB7 | Cofactors | All
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Q13485.R361C

Completed successfully

Protein, domain: Q13485 MH2

Interacting with: Q68DB7 MH2

PDB templates used: 1u7v_B, 1u7v_A

Seq identity: 0.881, 0.806 Model score: -0.509

ELASPIC ΔΔG: 0.531

ELASPIC2 (EL2) score: 2.484

Mutation in databases: UniProt, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.