ELASPIC home << Job #oncokb << Q13485.K428A
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q13485.K428A

Detailed results for job #oncokb produced by ELASPIC
Q13485, Mothers against decapentaplegic homolog 4:
K428A
1
552
MH1
MH2
SKI, Ski oncogene:
1
728
c-SKI_SM..
Ski_Sno
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Protein: Q13485 | SKI | Cofactors | All
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Q13485.K428A

Completed successfully

Protein, domain: Q13485 MH2

Interacting with: SKI c-SKI_SMAD_bind

PDB templates used: 1mr1_A, 1mr1_D

Seq identity: 0.867, 0.990 Model score: 0.668

ELASPIC ΔΔG: 6.094

ELASPIC2 (EL2) score: 2.180

Mutation run by user.

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Citation

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