ELASPIC home << Job #oncokb << Q07864.P286R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q07864.P286R

Detailed results for job #oncokb produced by ELASPIC
Q07864, DNA polymerase epsilon catalytic subunit A:
P286R
1
2286
DNA_pol_B_exo1
DNA_pol_B

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Q07864.P286R

Completed successfully

Protein, domain: Q07864 DNA_pol_B_exo1

Type: Core (stability)

PDB template used: 4ptf_A

Seq identity: 0.541 Model score: -0.057

ELASPIC ΔΔG: -0.177

ELASPIC2 (EL2) score: 3.187

Mutation in databases: COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.