ELASPIC home << Job #oncokb << Q06187.Y551F
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

Q06187.Y551F

Detailed results for job #oncokb produced by ELASPIC
Q06187, Tyrosine-protein kinase BTK:
Y551F
1
659
PH+BTK
Pkinase_Tyr
SH3_1
SH2
PRKCB, Protein kinase C beta type:
1
671
C1_1
Pkinase+Pkinase_C
C1_1
C2
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Protein: Q06187 | PRKCB | Cofactors | All
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Q06187.Y551F

Completed successfully

Protein, domain: Q06187 Pkinase_Tyr

Interacting with: PRKCB Pkinase+Pkinase_C

PDB templates used: 2i0e_B, 2i0e_A

Seq identity: 0.258, 0.932 Model score: 0.221

ELASPIC ΔΔG: 0.316

ELASPIC2 (EL2) score: 0.741

Mutation run by user.

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Citation

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