ELASPIC home << Job #oncokb << Q06124.E139D
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

Q06124.E139D

Detailed results for job #oncokb produced by ELASPIC
Q06124, Tyrosine-protein phosphatase non-receptor type 11:
E139D
1
597
SH2
SH2
Y_phosphatase
PLCG1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1:
1
1290
SH2
SH2
S..
C2
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Protein: Q06124 | PLCG1 | Cofactors | All
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Q06124.E139D

Completed successfully

Protein, domain: Q06124 SH2

Interacting with: PLCG1 SH2

PDB templates used: 4k44_A, 4k44_B

Seq identity: 0.294, 1.000 Model score: -0.957

ELASPIC ΔΔG: 0.517

ELASPIC2 (EL2) score: 0.367

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

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