ELASPIC home << Job #oncokb << Q02750.S222D
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
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Q02750.S222D

Detailed results for job #oncokb produced by ELASPIC
Q02750, Dual specificity mitogen-activated protein kinase kinase 1:
S222D
1
393
Pkinase
RASH isoform 2, Isoform 2 of GTPase HRas:
1
170
Ras
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Q02750.S222D

Completed successfully

Protein, domain: Q02750 Pkinase

Interacting with: RASH isoform 2 Ras

PDB templates used: 2v55_C, 2v55_D

Seq identity: 0.324, 0.264 Model score: 1.006

ELASPIC ΔΔG: 0.437

ELASPIC2 (EL2) score: 1.375

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

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