ELASPIC home << Job #oncokb << Q02750.D65N
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q02750.D65N

Detailed results for job #oncokb produced by ELASPIC
Q02750, Dual specificity mitogen-activated protein kinase kinase 1:
D65N
1
393
Pkinase
GIT1 isoform 3, Isoform 3 of ARF GTPase-activating protein GIT1:
1
770
GIT1_C
ArfGap+Ank_2
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Q02750.D65N

Completed successfully

Protein, domain: Q02750 Pkinase

Interacting with: GIT1 isoform 3 ArfGap+Ank_2

PDB templates used: 1blx_A, 1blx_B

Seq identity: 0.278, 0.355 Model score: 2.406

ELASPIC ΔΔG: 0.118

ELASPIC2 (EL2) score: -0.059

Mutation run by user.

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Citation

If you use these results, please cite the papers on this page.