ELASPIC home << Job #oncokb << Q02080.Y69H
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q02080.Y69H

Detailed results for job #oncokb produced by ELASPIC
Q02080, Myocyte-specific enhancer factor 2B:
Y69H
1
365
SRF-TF
CABIN1, Calcineurin-binding protein cabin-1:
1
2220
TPR_11
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Model: Wild-type | Mutant | Both
Protein: Q02080 | CABIN1 | Cofactors | All
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Q02080.Y69H

Completed successfully

Protein, domain: Q02080 SRF-TF

Interacting with: CABIN1 MEF2_binding

PDB templates used: 1n6j_A, 1n6j_G

Seq identity: 1.000, 1.000 Model score: 0.084

ELASPIC ΔΔG: 1.184

ELASPIC2 (EL2) score: 1.534

Mutation in databases: COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.