ELASPIC home << Job #oncokb << Q02080.D83V
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

Q02080.D83V

Detailed results for job #oncokb produced by ELASPIC
Q02080, Myocyte-specific enhancer factor 2B:
D83V
1
365
SRF-TF
MEF2B isoform 2, Isoform 2 of Myocyte-specific enhancer factor 2B:
1
368
SRF-TF
Select affected interaction:

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Q02080.D83V

Completed successfully

Protein, domain: Q02080 SRF-TF

Interacting with: MEF2B isoform 2 SRF-TF

PDB templates used: 1n6j_A, 1n6j_B

Seq identity: 1.000, 1.000 Model score: -1.764

ELASPIC ΔΔG: 0.434

ELASPIC2 (EL2) score: 1.555

Mutation in databases: COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.