ELASPIC home << Job #oncokb << P78545.I279P
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P78545.I279P

Detailed results for job #oncokb produced by ELASPIC
P78545, ETS-related transcription factor Elf-3:
I279P
1
371
SAM_PNT
Ets
NFKB1 isoform 3, Isoform 3 of Nuclear factor NF-kappa-B p105 subunit:
1
788
Ank_2+Ank+Ank
Death
RHD
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P78545.I279P

Completed successfully

Protein, domain: P78545 Ets

Interacting with: NFKB1 isoform 3 Ank_2+Ank+Ank

PDB templates used: 1awc_A, 1awc_B

Seq identity: 0.439, 0.327 Model score: 1.639

ELASPIC ΔΔG: 0.822

ELASPIC2 (EL2) score: 1.439

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.