ELASPIC home << Job #oncokb << P63000.Q61R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P63000.Q61R

Detailed results for job #oncokb produced by ELASPIC
P63000, Ras-related C3 botulinum toxin substrate 1:
Q61R
1
192
Ras
DIAP1 isoform 2, Isoform 2 of Protein diaphanous homolog 1:
1
1248
FH2
D..
Drf_FH3+Drf_GBD
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P63000.Q61R

Completed successfully

Protein, domain: P63000 Ras

Interacting with: DIAP1 isoform 2 Drf_FH3+Drf_GBD

PDB templates used: 3eg5_A, 3eg5_B

Seq identity: 0.729, 0.901 Model score: -0.839

ELASPIC ΔΔG: 0.341

ELASPIC2 (EL2) score: 2.587

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

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