ELASPIC home << Job #oncokb << P63000.P29S
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P63000.P29S

Detailed results for job #oncokb produced by ELASPIC
P63000, Ras-related C3 botulinum toxin substrate 1:
P29S
1
192
Ras
DOCK8 isoform 3, Isoform 3 of Dedicator of cytokinesis protein 8:
1
2031
Ded_cyto
DOCK-C2
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P63000.P29S

Completed successfully

Protein, domain: P63000 Ras

Interacting with: DOCK8 isoform 3 Ded_cyto

PDB templates used: 3vhl_B, 3vhl_A

Seq identity: 0.718, 0.919 Model score: -0.988

ELASPIC ΔΔG: 2.891

ELASPIC2 (EL2) score: 0.730

Mutation in databases: COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.