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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P63000.P29L

Detailed results for job #oncokb produced by ELASPIC

P63000, Ras-related C3 botulinum toxin substrate 1:
P29L
1
192
DOCK8 isoform 2, Isoform 2 of Dedicator of cytokinesis protein 8:
1
2067
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P63000.P29L

Completed successfully

Protein, domain: P63000 Ras

Interacting with: DOCK8 isoform 2 Ded_cyto

PDB templates used: 3vhl_B, 3vhl_A

Seq identity: 0.718, 0.919 Model score: -0.988

ELASPIC ΔΔG: 0.846

ELASPIC2 (EL2) score: 1.464

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation


If you use these results, please cite the papers on this page.