ELASPIC home << Job #oncokb << P62070.Q72L
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P62070.Q72L

Detailed results for job #oncokb produced by ELASPIC
P62070, Ras-related protein R-Ras2:
Q72L
1
204
Ras
RIN1 isoform 2, Isoform RIN1-delta of Ras and Rab interactor 1:
1
721
VPS9
Select affected interaction:

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P62070.Q72L

Completed successfully

Protein, domain: P62070 Ras

Interacting with: RIN1 isoform 2 VPS9

PDB templates used: 2ot3_B, 2ot3_A

Seq identity: 0.306, 0.291 Model score: -0.465

ELASPIC ΔΔG: 1.272

ELASPIC2 (EL2) score: 2.665

Mutation in databases: UniProt, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.