ELASPIC home << Job #oncokb << P62070.Q72L
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P62070.Q72L

Detailed results for job #oncokb produced by ELASPIC
P62070, Ras-related protein R-Ras2:
Q72L
1
204
Ras
RASGRF1, Ras-specific guanine nucleotide-releasing factor 1:
1
1275
PH
RhoGEF
RasGEF_N+RasGEF
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Protein: P62070 | RASGRF1 | Cofactors | All
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P62070.Q72L

Completed successfully

Protein, domain: P62070 Ras

Interacting with: RASGRF1 RhoGEF

PDB templates used: 3bji_D, 3bji_A

Seq identity: 0.299, 0.235 Model score: -0.021

ELASPIC ΔΔG: 1.812

ELASPIC2 (EL2) score: 2.863

Mutation in databases: UniProt, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.