ELASPIC home << Job #oncokb << P61586.T37A
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
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P61586.T37A

Detailed results for job #oncokb produced by ELASPIC
P61586, Transforming protein RhoA:
T37A
1
193
Ras
ARHGEF11, Rho guanine nucleotide exchange factor 11:
1
1522
RGS-like
PDZ
RhoGEF
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Model: Wild-type | Mutant | Both
Protein: P61586 | ARHGEF11 | Cofactors | All
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P61586.T37A

Completed successfully

Protein, domain: P61586 Ras

Interacting with: ARHGEF11 RhoGEF

PDB templates used: 3qbv_C, 3qbv_D

Seq identity: 0.557, 0.302 Model score: -1.025

ELASPIC ΔΔG: 2.097

ELASPIC2 (EL2) score: 2.131

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.