ELASPIC home << Job #oncokb << P61586.T37A
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P61586.T37A

Detailed results for job #oncokb produced by ELASPIC
P61586, Transforming protein RhoA:
T37A
1
193
Ras
NGEF, Ephexin-1:
1
710
SH3_1
RhoGEF
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Protein: P61586 | NGEF | Cofactors | All
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P61586.T37A

Completed successfully

Protein, domain: P61586 Ras

Interacting with: NGEF RhoGEF

PDB templates used: 3qbv_C, 3qbv_D

Seq identity: 0.557, 0.283 Model score: -0.931

ELASPIC ΔΔG: 1.605

ELASPIC2 (EL2) score: 2.124

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

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