ELASPIC home << Job #oncokb << P61586.E40N
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P61586.E40N

Detailed results for job #oncokb produced by ELASPIC
P61586, Transforming protein RhoA:
E40N
1
193
Ras
DAAM1 isoform 2, Isoform 2 of Disheveled-associated activator of morphogenesis 1:
1
1068
Drf_GBD+Drf_FH3
FH2
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P61586.E40N

Completed successfully

Protein, domain: P61586 Ras

Interacting with: DAAM1 isoform 2 Drf_GBD+Drf_FH3

PDB templates used: 1z2c_C, 1z2c_D

Seq identity: 0.950, 0.291 Model score: 0.118

ELASPIC ΔΔG: -0.028

ELASPIC2 (EL2) score: 2.201

Mutation run by user.

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Citation

If you use these results, please cite the papers on this page.