ELASPIC home << Job #oncokb << P61586.E40N
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
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P61586.E40N

Detailed results for job #oncokb produced by ELASPIC
P61586, Transforming protein RhoA:
E40N
1
193
Ras
PKHG2 isoform 2, Isoform 2 of Pleckstrin homology domain-containing family G member 2:
1
577
RhoGEF
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P61586.E40N

Completed successfully

Protein, domain: P61586 Ras

Interacting with: PKHG2 isoform 2 RhoGEF

PDB templates used: 2rgn_C, 2rgn_B

Seq identity: 1.000, 0.343 Model score: -0.912

ELASPIC ΔΔG: -0.026

ELASPIC2 (EL2) score: 2.584

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.