ELASPIC home << Job #oncokb << P61586.E40N
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P61586.E40N

Detailed results for job #oncokb produced by ELASPIC
P61586, Transforming protein RhoA:
E40N
1
193
Ras
DOCK7, Dedicator of cytokinesis protein 7:
1
2140
Ded_cyto
DOCK..
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Protein: P61586 | DOCK7 | Cofactors | All
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P61586.E40N

Completed successfully

Protein, domain: P61586 Ras

Interacting with: DOCK7 Ded_cyto

PDB templates used: 3vhl_B, 3vhl_A

Seq identity: 0.546, 0.736 Model score: -1.073

ELASPIC ΔΔG: -0.088

ELASPIC2 (EL2) score: 1.678

Mutation run by user.

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Citation

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