ELASPIC home << Job #oncokb << P61586.E40L
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
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P61586.E40L

Detailed results for job #oncokb produced by ELASPIC
P61586, Transforming protein RhoA:
E40L
1
193
Ras
RASGRF1, Ras-specific guanine nucleotide-releasing factor 1:
1
1275
PH
RhoGEF
RasGEF_N+RasGEF
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Model: Wild-type | Mutant | Both
Protein: P61586 | RASGRF1 | Cofactors | All
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P61586.E40L

Completed successfully

Protein, domain: P61586 Ras

Interacting with: RASGRF1 RhoGEF

PDB templates used: 3bji_D, 3bji_A

Seq identity: 0.573, 0.235 Model score: -0.469

ELASPIC ΔΔG: 0.519

ELASPIC2 (EL2) score: 1.995

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.