ELASPIC home << Job #oncokb << P61586.E40L
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P61586.E40L

Detailed results for job #oncokb produced by ELASPIC
P61586, Transforming protein RhoA:
E40L
1
193
Ras
RHOA, Transforming protein RhoA:
1
193
Ras
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Protein: P61586 | RHOA | Cofactors | All
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P61586.E40L

Completed successfully

Protein, domain: P61586 Ras

Interacting with: RHOA Ras

PDB templates used: 2p2l_B, 2p2l_C

Seq identity: 0.592, 0.598 Model score: -0.944

ELASPIC ΔΔG: 0.107

ELASPIC2 (EL2) score: 2.318

Mutation run by user.

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Citation

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