ELASPIC home << Job #oncokb << P52701.V509A
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P52701.V509A

Detailed results for job #oncokb produced by ELASPIC
P52701, DNA mismatch repair protein Msh6:
V509A
1
1360
PWWP
MutS_I
MutS_II
MutS_III+MutS_V

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P52701.V509A

Completed successfully

Protein, domain: P52701 MutS_I

Type: Core (stability)

PDB template used: 1ng9_A

Seq identity: 0.281 Model score: 0.848

ELASPIC ΔΔG: 0.869

ELASPIC2 (EL2) score: 0.208

Mutation in databases: UniProt, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.