ELASPIC home << Job #oncokb << P49815.G1596V
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P49815.G1596V

Detailed results for job #oncokb produced by ELASPIC
P49815, Tuberin:
G1596V
1
1807
Rap_GAP
RAB5A, Ras-related protein Rab-5A:
1
215
Ras
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Model: Wild-type | Mutant | Both
Protein: P49815 | RAB5A | Cofactors | All
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P49815.G1596V

Completed successfully

Protein, domain: P49815 Rap_GAP

Interacting with: RAB5A Ras

PDB templates used: 3brw_B, 3brw_D

Seq identity: 0.315, 0.343 Model score: 0.145

ELASPIC ΔΔG: 2.338

ELASPIC2 (EL2) score: 2.189

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.