ELASPIC home << Job #oncokb << P42772.D86N
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P42772.D86N

Detailed results for job #oncokb produced by ELASPIC
P42772, Cyclin-dependent kinase 4 inhibitor B:
D86N
1
138
Ank_2
CDK8 isoform 2, Isoform 2 of Cyclin-dependent kinase 8:
1
463
Pkinase
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P42772.D86N

Completed successfully

Protein, domain: P42772 Ank_2

Interacting with: CDK8 isoform 2 Pkinase

PDB templates used: 1bi7_B, 1bi7_A

Seq identity: 0.869, 0.330 Model score: 0.950

ELASPIC ΔΔG: 1.576

ELASPIC2 (EL2) score: -0.332

Mutation run by user.

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Citation

If you use these results, please cite the papers on this page.