ELASPIC home << Job #oncokb << P42771.D84H
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P42771.D84H

Detailed results for job #oncokb produced by ELASPIC
P42771, Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3:
D84H
1
156
Ank
MK10 isoform 3, Isoform 3 of Mitogen-activated protein kinase 10:
1
426
Pkinase
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P42771.D84H

Completed successfully

Protein, domain: P42771 Ank

Interacting with: MK10 isoform 3 Pkinase

PDB templates used: 1bi7_B, 1bi7_A

Seq identity: 0.992, 0.341 Model score: 0.693

ELASPIC ΔΔG: 0.863

ELASPIC2 (EL2) score: -0.407

Mutation in databases: UniProt, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.