ELASPIC home << Job #oncokb << P42338.E552K
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P42338.E552K

Detailed results for job #oncokb produced by ELASPIC
P42338, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform:
E552K
1
1070
PI3_PI4_kinase
PI3K_p85B+PI3K_rbd
PI3K_C2+PI3Ka

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P42338.E552K

Completed successfully

Protein, domain: P42338 PI3K_C2+PI3Ka

Type: Core (stability)

PDB template used: 2wxk_A

Seq identity: 0.549 Model score: 0.652

ELASPIC ΔΔG: -3.858

ELASPIC2 (EL2) score: 0.458

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.