ELASPIC home << Job #oncokb << P40337.C162F
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
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P40337.C162F

Detailed results for job #oncokb produced by ELASPIC
P40337, Von Hippel-Lindau disease tumor suppressor:
C162F
1
213
VHL
TCEB1, Transcription elongation factor B polypeptide 1:
1
112
Skp1_POZ
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Model: Wild-type | Mutant | Both
Protein: P40337 | TCEB1 | Cofactors | All
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P40337.C162F

Completed successfully

Protein, domain: P40337 VHL

Interacting with: TCEB1 Skp1_POZ

PDB templates used: 4ajy_V, 4ajy_C

Seq identity: 1.000, 0.917 Model score: -1.456

ELASPIC ΔΔG: 3.466

ELASPIC2 (EL2) score: 1.062

Mutation in databases: UniProt, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.