ELASPIC home << Job #oncokb << P38398.P1812R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P38398.P1812R

Detailed results for job #oncokb produced by ELASPIC
P38398, Breast cancer type 1 susceptibility protein:
P1812R
1
1863
zf..
BRCT
Q1RMC1, BRCA1 protein:
1
1354
BRCT
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Protein: P38398 | Q1RMC1 | Cofactors | All
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P38398.P1812R

Completed successfully

Protein, domain: P38398 BRCT

Interacting with: Q1RMC1 BRCT

PDB templates used: 3pxe_C, 3pxe_B

Seq identity: 0.986, 0.991 Model score: -0.899

ELASPIC ΔΔG: 2.803

ELASPIC2 (EL2) score: 0.603

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.