ELASPIC home << Job #oncokb << P38398.N1819S
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P38398.N1819S

Detailed results for job #oncokb produced by ELASPIC
P38398, Breast cancer type 1 susceptibility protein:
N1819S
1
1863
zf..
BRCT
BRCA1, Breast cancer type 1 susceptibility protein:
1
1863
zf..
BRCT
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Protein: P38398 | BRCA1 | Cofactors | All
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P38398.N1819S

Completed successfully

Protein, domain: P38398 BRCT

Interacting with: BRCA1 BRCT

PDB templates used: 3pxe_C, 3pxe_B

Seq identity: 0.986, 0.995 Model score: -0.884

ELASPIC ΔΔG: 3.468

ELASPIC2 (EL2) score: -1.827

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.