ELASPIC home << Job #oncokb << P38398.L63F
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P38398.L63F

Detailed results for job #oncokb produced by ELASPIC
P38398, Breast cancer type 1 susceptibility protein:
L63F
1
1863
zf..
BRCT
UBE2N, Ubiquitin-conjugating enzyme E2 N:
1
152
UQ_con
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Protein: P38398 | UBE2N | Cofactors | All
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P38398.L63F

Completed successfully

Protein, domain: P38398 zf-C3HC4

Interacting with: UBE2N UQ_con

PDB templates used: 3hct_A, 3hct_B

Seq identity: 0.391, 1.000 Model score: -0.349

ELASPIC ΔΔG: 0.905

ELASPIC2 (EL2) score: 0.223

Mutation run by user.

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Citation

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