ELASPIC home << Job #oncokb << P38398.L52F
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P38398.L52F

Detailed results for job #oncokb produced by ELASPIC
P38398, Breast cancer type 1 susceptibility protein:
L52F
1
1863
zf..
BRCT
Q96FI0, UBE2W protein:
1
159
UQ_con
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Model: Wild-type | Mutant | Both
Protein: P38398 | Q96FI0 | Cofactors | All
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P38398.L52F

Completed successfully

Protein, domain: P38398 zf-C3HC4

Interacting with: Q96FI0 UQ_con

PDB templates used: 3rpg_C, 3rpg_A

Seq identity: 0.347, 0.371 Model score: 0.440

ELASPIC ΔΔG: 0.526

ELASPIC2 (EL2) score: -1.382

Mutation run by user.

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Citation

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