ELASPIC home << Job #oncokb << P38398.K56N
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P38398.K56N

Detailed results for job #oncokb produced by ELASPIC
P38398, Breast cancer type 1 susceptibility protein:
K56N
1
1863
zf..
BRCT
A8K503, cDNA FLJ76182, highly similar to Homo sapiens ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) (UBE2I), transcript variant 1, mRNA:
1
158
UQ_con
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Protein: P38398 | A8K503 | Cofactors | All
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P38398.K56N

Completed successfully

Protein, domain: P38398 zf-C3HC4

Interacting with: A8K503 UQ_con

PDB templates used: 3rpg_C, 3rpg_A

Seq identity: 0.347, 0.357 Model score: 0.156

ELASPIC ΔΔG: 0.837

ELASPIC2 (EL2) score: -0.708

Mutation run by user.

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Citation

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