ELASPIC home << Job #oncokb << P38398.I42V
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P38398.I42V

Detailed results for job #oncokb produced by ELASPIC
P38398, Breast cancer type 1 susceptibility protein:
I42V
1
1863
zf..
BRCT
RAD18, E3 ubiquitin-protein ligase RAD18:
1
495
zf-C3HC4
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Protein: P38398 | RAD18 | Cofactors | All
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P38398.I42V

Completed successfully

Protein, domain: P38398 zf-C3HC4

Interacting with: RAD18 zf-C3HC4

PDB templates used: 1jm7_A, 1jm7_B

Seq identity: 1.000, 0.293 Model score: -0.082

ELASPIC ΔΔG: 2.544

ELASPIC2 (EL2) score: -0.317

Mutation run by user.

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Citation

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